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安雅·希拉里博士.D.


Department of Health Sciences, Nursing and Public Health


教育

B.Sc. (制药acy) (First Class Honours; awarded the Trinity College Gold Medal for Outstanding Achievement), School of 制药acy and 制药aceutical Sciences, Trinity 都柏林学院,都柏林,爱尔兰.
Ph.D. (制药aceutics), Centre for Drug Delivery Research, University College London School of 制药acy, Brunswick Square, London, UK.

实践领域

  • 给药系统
  • 药物的靶向
  • 脂质体

研究兴趣

惠康信托基金. 项目补助金(16万英镑).
The development of synthetic peptide vaccines, using a novel polymeric vaccine-adjuvant 基于脂胺基酸的缀合物.

惠康信托基金. 新讲师补助金(61,010英镑)
Particle-forming properties of lipoamino acid - based systems and their potential use as particulate carriers for oral vaccination using peptide antigens.

利比亚政府. 研究奖学金(6万英镑)
Formulation of novel anaesthetic gels for bladder catheterisation.

出版物和媒体投放


Drug Delivery: Fundamentals and Applications, Second Edition
希拉里·AM,帕克·K,编.) 2016.
CRC新闻/泰勒 & 弗朗西斯集团. 佛罗里达州的博卡拉顿.
ISBN 978 - 1482217711

Drug Delivery and 针对 for 制药acists and 制药aceutical Scientists
Hillery AM, Lloyd AW, Swarbrick J, (eds.) 2001.
泰勒和弗朗西斯,伦敦.
ISBN 0-415-27197-5.

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期刊文章:原创研究

希拉里·安,贾尼·普,弗洛伦斯·AT. Comparative quantitative study of lymphoid and non- lymphoid uptake of 50nm polystyrene particles. J Drug Target 1994; 2: 151-156.

Toth I, Hillery AM, Wood I, Magnusson C, Artursson P. 脂质氨基的口服吸收 酸配合. Int J 制药 1994; 102: 223-230.

Toth I, Flinn N, Hillery AM, Artursson P. Lipidic conjugates of luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH) that release and protect the native hormones in homogenates of human intestinal epithelial (Caco-2) 细胞. Int J 制药 1994; 105: 241-247.

Toth I, Hillery AM, Hughes RA, Dekany G, Ward P. 脂质多肽. 合成和 oral uptake studies of lipidic and glyco-lipidic conjugates of ß-lactam antibiotics. 利布安化学. 1994; 7: 685-688.

Flinn N, Danton M, Hillery AM, Wood I, Gibbons WA, Toth I. 一种脂质氨基酸 carrier adjuvant system for drug delivery and for enhancing synthetic peptide immunogenicity. Biochem Soc Trans 1994; 22: 1055-1058.

Florence AT, Hillery AM, Hussain N, Jani PU. Oral uptake and translocation of nanoparticles: 一个真实但有用的现象? In: Gregoriadis G, McCormack B, Poste G. eds. 针对 of Drugs: Advances in System Constructs. New York: Plenum Press, 1994, pp 173-181.

Florence AT, Hillery AM, Hussain N, Jani PU. Factors affecting the oral uptake and translocation of polystyrene nanoparticles: histological and analytical evidence. J Drug Target 1995; 3: 65-70.

Florence AT, Hillery AM, Hussain N, Jani PU. Nanoparticles as carriers for oral peptide absorption: studies on particle uptake and fate. J Control Rel 1995; 36: 39-46.

我是希拉里,弗洛伦斯报道. The effect of adsorbed poloxamer surfactants on the intestinal uptake of 60 nm polyetyrene particles after oral administration in the rat. Int J 制药 1996; 132: 123-130.

希拉里,托特,佛罗伦斯. Co-polymerised peptide particles (CPP) I: synthesis, characterization and in vitro studies on a novel oral nanoparticulate delivery system. J控制杂志1996; 41: 271-281.

希拉里,托特,佛罗伦斯. Co-polymerised peptide particles (CPP) II: oral uptake of a novel co-polymeric LHRH nanoparticulate delivery system. J控制杂志1996; 42: 65-73.

希拉里,托特,佛罗伦斯. Biological activity of luteinizing hormone releasing hormone after oral dosing with a novel delivery system: Co-Polymerized Peptide Particles (CPP). 制药科学 1996; 2: 281-283.

Drouillat B, Hillery AM, Dekany G, Falconer R, Wright K, Toth I. 小说liposaccharide conjugates for drug and peptide delivery. J 制药科学 1998; 87:25-30.

期刊评论文章

Hillery AM, Supramolecular lipidic drug delivery systems: from laboratory to clinic. A review of the recently introduced commercial liposomal and lipid-based formulations 两性霉素B. Adv Drug Del Rev 1997; 24:345-363.

希拉里AM,连续v. 不连续的治疗. 《博彩网址大全》. 4月1998; 1 (1).

Hillery AM, Microparticulate delivery systems: potential drug/vaccine carriers via 粘膜的路线. 《博彩网址大全》. 五月 1998; 1 (2).

Hillery AM, Liposomal drug delivery (I) Introduction. 制药 J; 10月 1998; 626-629.

Hillery AM, Liposomal drug delivery (II) Clinical Applications. 制药 J; 10月 1998; 712-715.

Hillery AM, Novel vaccine strategy demonstrates potential for Alzheimer's disease. 《博彩网址大全》. Sept 1999; 2 (9).

Hillery AM, New therapeutic options for HIV patients. 《博彩网址大全》. 10月 1999; 2 (10).

Hillery AM, Tumour-killing herpes simplex virus - a promising new approach for brain 癌症. 《博彩网址大全》. 10月 1999; 2 (10).

Hillery AM, Haemophilia B gene therapy using adeno-associated virus. 制药科学与技术 今天. Nov 1999; 2 (11).

Hillery AM, Anti-vascular targeting: a novel approach to 癌症 treatment. 制药科学 今天的技术. Jan 2000; 3 (1).

Hillery AM, New implant device for Alzheimer's treatment. 《博彩网址大全》. Feb 2000; 3 (2).

Hillery AM, BioArtificial Muscle implants as drug delivery systems. 制药科学技术 今天. 3月 2000; 3 (3).

Hillery AM, New liposomal formulation of vincristine for non-Hodgkin's lymphoma. 制药 科技今日. 3月 2000; 3 (3).

Hillery AM, Computer-integrated drug design provides new leads for thromboembolic 障碍. 《博彩网址大全》. April 2000; 3 (4).

Hillery AM, New first-line monotherapy for epilepsy. 《博彩网址大全》. 五月 2000; 3 (5).

Hillery AM, Mouse model for Burkitt's lymphoma will aid understanding and therapy. 今日药物发现. Jan 2001; 6 (1).

Hillery AM, 针对 ‘good' cholesterol to treat heart disease. 今日药物发现. Feb 2001; 6 (3).

Hillery AM, Heat-sensitive liposomes for tumour targeting. 今日药物发现. 3月 2001; 6 (5).

荣誉及奖励

Maplethorpe Fellowship Award in the 制药aceutical Sciences (1/10/1994): 2 years funding 博士后研究.

Controlled Release Society Award: best presentation at the UK CRS Symposium on Controlled 药物递送(8/1/1996).

Syntex Research (UK) Ltd: PhD Scholarship Award (1/10/1991).

Trinity College Gold Medal for Outstanding Achievement: best overall results in Trinity College Dublin 1990 Final-Year Examinations (1/7/1990).

Janssen Silver Medal: best final-year project (on the action of blockers at the neuromuscular junction) in the BSc (制药acy) Examinations (1/7/1990).